Expressing:Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer.
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Deciphering the role of immunoglobulin secreting malignant lineages in the invasive frontiers of small cell lung cancer by scRNA-seq and spatial transcriptomics analysis
Article Snippet: The human SCLC cell lines DMS53, NCI-H146, NCI-H524, NCI-H526, and SW1271 were obtained from American Type Culture Collection (ATCC), all cell lines were authenticated by short tandem repeat (STR) profiling and has been tested for mycoplasma contamination.. SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.
Article Title: YES1 Is a Druggable Oncogenic Target in SCLC.
Article Snippet: Human SCLC cell lines DMS53, H209, H446, H82, H187, H1963, N417, CORL88, H1436, and H69 cells were obtained from American Type Culture Collection (Manassas, Virginia).. H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).
In Vitro:Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer.
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Deciphering the role of immunoglobulin secreting malignant lineages in the invasive frontiers of small cell lung cancer by scRNA-seq and spatial transcriptomics analysis
Article Snippet: The human SCLC cell lines DMS53, NCI-H146, NCI-H524, NCI-H526, and SW1271 were obtained from American Type Culture Collection (ATCC), all cell lines were authenticated by short tandem repeat (STR) profiling and has been tested for mycoplasma contamination.. SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.
Article Title: YES1 Is a Druggable Oncogenic Target in SCLC.
Article Snippet: Human SCLC cell lines DMS53, H209, H446, H82, H187, H1963, N417, CORL88, H1436, and H69 cells were obtained from American Type Culture Collection (Manassas, Virginia).. H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).
Inhibition:Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer.
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Deciphering the role of immunoglobulin secreting malignant lineages in the invasive frontiers of small cell lung cancer by scRNA-seq and spatial transcriptomics analysis
Article Snippet: The human SCLC cell lines DMS53, NCI-H146, NCI-H524, NCI-H526, and SW1271 were obtained from American Type Culture Collection (ATCC), all cell lines were authenticated by short tandem repeat (STR) profiling and has been tested for mycoplasma contamination.. SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.
Article Title: YES1 Is a Druggable Oncogenic Target in SCLC.
Article Snippet: Human SCLC cell lines DMS53, H209, H446, H82, H187, H1963, N417, CORL88, H1436, and H69 cells were obtained from American Type Culture Collection (Manassas, Virginia).. H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).
shRNA:Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer.
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Deciphering the role of immunoglobulin secreting malignant lineages in the invasive frontiers of small cell lung cancer by scRNA-seq and spatial transcriptomics analysis
Article Snippet: The human SCLC cell lines DMS53, NCI-H146, NCI-H524, NCI-H526, and SW1271 were obtained from American Type Culture Collection (ATCC), all cell lines were authenticated by short tandem repeat (STR) profiling and has been tested for mycoplasma contamination.. SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.
Article Title: YES1 Is a Druggable Oncogenic Target in SCLC.
Article Snippet: Human SCLC cell lines DMS53, H209, H446, H82, H187, H1963, N417, CORL88, H1436, and H69 cells were obtained from American Type Culture Collection (Manassas, Virginia).. H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).
Control:Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer.
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Deciphering the role of immunoglobulin secreting malignant lineages in the invasive frontiers of small cell lung cancer by scRNA-seq and spatial transcriptomics analysis
Article Snippet: The human SCLC cell lines DMS53, NCI-H146, NCI-H524, NCI-H526, and SW1271 were obtained from American Type Culture Collection (ATCC), all cell lines were authenticated by short tandem repeat (STR) profiling and has been tested for mycoplasma contamination.. SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.
Article Title: YES1 Is a Druggable Oncogenic Target in SCLC.
Article Snippet: Human SCLC cell lines DMS53, H209, H446, H82, H187, H1963, N417, CORL88, H1436, and H69 cells were obtained from American Type Culture Collection (Manassas, Virginia).. H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).
Staining:Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer.
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Deciphering the role of immunoglobulin secreting malignant lineages in the invasive frontiers of small cell lung cancer by scRNA-seq and spatial transcriptomics analysis
Article Snippet: The human SCLC cell lines DMS53, NCI-H146, NCI-H524, NCI-H526, and SW1271 were obtained from American Type Culture Collection (ATCC), all cell lines were authenticated by short tandem repeat (STR) profiling and has been tested for mycoplasma contamination.. SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.
Article Title: YES1 Is a Druggable Oncogenic Target in SCLC.
Article Snippet: Human SCLC cell lines DMS53, H209, H446, H82, H187, H1963, N417, CORL88, H1436, and H69 cells were obtained from American Type Culture Collection (Manassas, Virginia).. H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).
Derivative Assay:Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer.
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Deciphering the role of immunoglobulin secreting malignant lineages in the invasive frontiers of small cell lung cancer by scRNA-seq and spatial transcriptomics analysis
Article Snippet: The human SCLC cell lines DMS53, NCI-H146, NCI-H524, NCI-H526, and SW1271 were obtained from American Type Culture Collection (ATCC), all cell lines were authenticated by short tandem repeat (STR) profiling and has been tested for mycoplasma contamination.. SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.
Article Title: YES1 Is a Druggable Oncogenic Target in SCLC.
Article Snippet: Human SCLC cell lines DMS53, H209, H446, H82, H187, H1963, N417, CORL88, H1436, and H69 cells were obtained from American Type Culture Collection (Manassas, Virginia).. H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).
Clinical Proteomics:Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer.
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Deciphering the role of immunoglobulin secreting malignant lineages in the invasive frontiers of small cell lung cancer by scRNA-seq and spatial transcriptomics analysis
Article Snippet: The human SCLC cell lines DMS53, NCI-H146, NCI-H524, NCI-H526, and SW1271 were obtained from American Type Culture Collection (ATCC), all cell lines were authenticated by short tandem repeat (STR) profiling and has been tested for mycoplasma contamination.. SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.
Article Title: YES1 Is a Druggable Oncogenic Target in SCLC.
Article Snippet: Human SCLC cell lines DMS53, H209, H446, H82, H187, H1963, N417, CORL88, H1436, and H69 cells were obtained from American Type Culture Collection (Manassas, Virginia).. H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).
Extraction:Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer.
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Deciphering the role of immunoglobulin secreting malignant lineages in the invasive frontiers of small cell lung cancer by scRNA-seq and spatial transcriptomics analysis
Article Snippet: The human SCLC cell lines DMS53, NCI-H146, NCI-H524, NCI-H526, and SW1271 were obtained from American Type Culture Collection (ATCC), all cell lines were authenticated by short tandem repeat (STR) profiling and has been tested for mycoplasma contamination.. SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.
Article Title: YES1 Is a Druggable Oncogenic Target in SCLC.
Article Snippet: Human SCLC cell lines DMS53, H209, H446, H82, H187, H1963, N417, CORL88, H1436, and H69 cells were obtained from American Type Culture Collection (Manassas, Virginia).. H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).
Western Blot:Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer.
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Deciphering the role of immunoglobulin secreting malignant lineages in the invasive frontiers of small cell lung cancer by scRNA-seq and spatial transcriptomics analysis
Article Snippet: The human SCLC cell lines DMS53, NCI-H146, NCI-H524, NCI-H526, and SW1271 were obtained from American Type Culture Collection (ATCC), all cell lines were authenticated by short tandem repeat (STR) profiling and has been tested for mycoplasma contamination.. SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.
Article Title: YES1 Is a Druggable Oncogenic Target in SCLC.
Article Snippet: Human SCLC cell lines DMS53, H209, H446, H82, H187, H1963, N417, CORL88, H1436, and H69 cells were obtained from American Type Culture Collection (Manassas, Virginia).. H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).
Isolation:Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer.
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Deciphering the role of immunoglobulin secreting malignant lineages in the invasive frontiers of small cell lung cancer by scRNA-seq and spatial transcriptomics analysis
Article Snippet: The human SCLC cell lines DMS53, NCI-H146, NCI-H524, NCI-H526, and SW1271 were obtained from American Type Culture Collection (ATCC), all cell lines were authenticated by short tandem repeat (STR) profiling and has been tested for mycoplasma contamination.. SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.
Article Title: YES1 Is a Druggable Oncogenic Target in SCLC.
Article Snippet: Human SCLC cell lines DMS53, H209, H446, H82, H187, H1963, N417, CORL88, H1436, and H69 cells were obtained from American Type Culture Collection (Manassas, Virginia).. H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).
Electron Microscopy:Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer.
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Deciphering the role of immunoglobulin secreting malignant lineages in the invasive frontiers of small cell lung cancer by scRNA-seq and spatial transcriptomics analysis
Article Snippet: The human SCLC cell lines DMS53, NCI-H146, NCI-H524, NCI-H526, and SW1271 were obtained from American Type Culture Collection (ATCC), all cell lines were authenticated by short tandem repeat (STR) profiling and has been tested for mycoplasma contamination.. SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.
Article Title: YES1 Is a Druggable Oncogenic Target in SCLC.
Article Snippet: Human SCLC cell lines DMS53, H209, H446, H82, H187, H1963, N417, CORL88, H1436, and H69 cells were obtained from American Type Culture Collection (Manassas, Virginia).. H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).
Immunohistochemistry:Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer.
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Deciphering the role of immunoglobulin secreting malignant lineages in the invasive frontiers of small cell lung cancer by scRNA-seq and spatial transcriptomics analysis
Article Snippet: The human SCLC cell lines DMS53, NCI-H146, NCI-H524, NCI-H526, and SW1271 were obtained from American Type Culture Collection (ATCC), all cell lines were authenticated by short tandem repeat (STR) profiling and has been tested for mycoplasma contamination.. SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.
Article Title: YES1 Is a Druggable Oncogenic Target in SCLC.
Article Snippet: Human SCLC cell lines DMS53, H209, H446, H82, H187, H1963, N417, CORL88, H1436, and H69 cells were obtained from American Type Culture Collection (Manassas, Virginia).. H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).
Knockdown:Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Integrative epigenome and transcriptome analyses reveal transcriptional programs differentially regulated by ASCL1 and NEUROD1 in small cell lung cancer.
Article Snippet: Human SCLC cell lines DMS53, DMS454, and H2066 were purchased from ATCC (Manassas, VA, USA).. Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).Additionally, Lu134A and WA-hT cells were obtained from RIKEN BRC (Tsukuba, Japan), and CORL279 was purchased from ECACC (Porton Down, Salisbury, UK).
Article Title: Deciphering the role of immunoglobulin secreting malignant lineages in the invasive frontiers of small cell lung cancer by scRNA-seq and spatial transcriptomics analysis
Article Snippet: The human SCLC cell lines DMS53, NCI-H146, NCI-H524, NCI-H526, and SW1271 were obtained from American Type Culture Collection (ATCC), all cell lines were authenticated by short tandem repeat (STR) profiling and has been tested for mycoplasma contamination.. SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.SW1271 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) basic medium supplemented with 10% Fetal Bovine Serum (FBS; Gibco), 100 U/mL penicillin, and 100 µg/mL streptomycin, while others were were cultured in RPMI1640 and supplemented with the aforementioned components.
Article Title: YES1 Is a Druggable Oncogenic Target in SCLC.
Article Snippet: Human SCLC cell lines DMS53, H209, H446, H82, H187, H1963, N417, CORL88, H1436, and H69 cells were obtained from American Type Culture Collection (Manassas, Virginia).. H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).H209 and H69 cells were cultured in RPMI-1640 (Gibco) supplemented with 10% HyClone serum (Thermo Fisher Scientific, Waltham, Massachusetts) and 1% penicillin-streptomycin (Lonza Group AG, Basel, Switzerland).
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